European Journal of Radiology
Volume 73, Issue 2 , Pages 288-293 , February 2010

Contrast-enhanced ultrasound is helpful in the differentiation of malignant and benign breast lesions

  • Hongjia Zhao

      Affiliations

    • Department of Ultrasound, The Second Affiliated Hospital of Fujian University of Traditional Chinese Medicine, Fuzhou, China
  • ,
  • Rong Xu

      Affiliations

    • Department of Ultrasound, The Second Affiliated Hospital of Fujian University of Traditional Chinese Medicine, Fuzhou, China
  • ,
  • Qiufang Ouyang

      Affiliations

    • Department of Ultrasound, The Second Affiliated Hospital of Fujian University of Traditional Chinese Medicine, Fuzhou, China
  • ,
  • Lidian Chen

      Affiliations

    • Fujian University of Traditional Chinese Medicine, Fuzhou, China
    • Corresponding Author InformationCorresponding author. Tel.: +86 591 22861985; fax: +86 591 22861989.
  • ,
  • Baowei Dong

      Affiliations

    • Department of Ultrasound, PLA 301 General Hospital, Beijing, China
  • ,
  • Ye Huihua

      Affiliations

    • Department of Ultrasound, The Second Affiliated Hospital of Fujian University of Traditional Chinese Medicine, Fuzhou, China

Received 29 December 2008 ,Revised 20 May 2009 ,Accepted 26 May 2009.

References 

  1. Folkman J. Angiogenesis and breast cancer. J Clin Oncol. 1994;12:441–443
  2. Ricci P, Cantisani V, Ballesio L, et al. Benign and malignant breast lesions: efficacy of real time contrast-enhanced ultrasound vs. magnetic resonance imaging. Ultraschall Med. 2007;28(1):57–62
  3. Barnard S, Leen E, Cooke T, Angerson W. A contrast-enhanced ultrasound study of benign and malignant breast tissue. S Afr Med J. 2008;98(5):386–391
  4. Kettenbach J, Helbich TH, Huber S, Zuna I, Dock W. Computer-assisted quantitative assessment of power Doppler US: effects of microbubble contrast agent in the differentiation of breast tumors. Eur Radiol. 2005;53(2):238–244
  5. Hochmuth A, Boehm T, Bitzer C, Fleck M, Schneider A, Kaiser WA. Differentiation of breast masses using 3-D sonographic and echo-enhancer-based evaluation of the vascular pattern: initial experiences. Ultrasound Med Biol. 2002;28(7):845–851
  6. Tozaki M, Igarashi T, Matsushima S, et al. High-spatial-resolution MR imaging of focal breast masses: interpretation model based on kinetic and morphological parameters. Radiat Med. 2005;23(1):43–50
  7. Teifke A, Lehr HA, Vomweg TW, et al. Outcome analysis and rational management of enhancing lesions incidentally detected on contrast-enhanced MRI of the breast. AJR Am J Roentgenol. 2003;181(3):655–662
  8. Stuhrmann M, Aronius R, Schietzel M . Tumor vascularity of breast lesions: potentials and limits of contrast-enhanced Doppler sonography. AJR Am J Roentgenol. 2000;75(6):1585–1589
  9. Ozdemir A, Kilic K, Ozdemir H, et al. Contrast-enhanced power Doppler sonography in breast lesions: effect on differential diagnosis after mammography and gray scale sonography. J Ultrasound Med. 2004;23(2):183–195
  10. Shubik P. Vascularization of tumors: a review. J Cancer Res Clin Oncol. 1982;103:211–226
  11. Menna S, Divirgilio MR, Burke P. Ultrasonography contrast media Levovist and power Doppler in the study of the breast: methodology, vascular morphology and automatic enhancement quantification with wash-in and wash-out curves. Radiol Med (Torino). 1999;97:472–478
  12. Boyajian RA, Otis SM, Droste DW, et al. Continuous infusion versus bolus injection of ultrasound contrast agents in vascular doppler flow imaging response. Stroke. 2000;31(9):2266–2278

PII: S0720-048X(09)00342-8

doi: 10.1016/j.ejrad.2009.05.043

European Journal of Radiology
Volume 73, Issue 2 , Pages 288-293 , February 2010