European Journal of Radiology
Volume 64, Issue 3 , Pages 414-418, December 2007

Magnetic resonance spectroscopy as a diagnostic modality for carcinoma thyroid

  • Nikhil Gupta

      Affiliations

    • Department of Surgery, Maulana Azad Medical College, Lok Nayak Hospital, New Delhi, India
    • Corresponding Author InformationCorresponding author. Tel.: +91 11 45526090.
    • ,
  • Arun K. Kakar

      Affiliations

    • Department of Surgery, Maulana Azad Medical College, Lok Nayak Hospital, New Delhi, India
    • ,
  • Veena Chowdhury

      Affiliations

    • Department of Radiodiagnosis, Maulana Azad Medical College, Lok Nayak Hospital, New Delhi, India
    • ,
  • Praveen Gulati

      Affiliations

    • MR Centre, A-23 Green Park, New Delhi, India
    • ,
  • L. Ravi Shankar

      Affiliations

    • Department of Radioiodine Uptake and Imaging, Institute of Nucler Medicine and Allied Sciences (INMAS), Timarpur, New Delhi, India
    • ,
  • Anubhav Vindal

      Affiliations

    • Department of Surgery, Maulana Azad Medical College, Lok Nayak Hospital, New Delhi, India

Received 18 May 2006; received in revised form 16 December 2006; accepted 9 March 2007.

Abstract 

Aim

The aim of this study was to observe the findings of magnetic resonance spectroscopy of solitary thyroid nodules and its correlation with histopathology.

Materials and methods

In this study, magnetic resonance spectroscopy was carried out on 26 patients having solitary thyroid nodules. Magnetic resonance spectroscopy (MRS) was performed on a 1.5T super conductive system with gradient strength of 33mTs. Fine needle aspiration cytology was done after MRS. All 26 patients underwent surgery either because of cytopathologically proven malignancy or because of cosmetic reasons. Findings of magnetic resonance spectroscopy were compared with histopathology of thyroid specimens.

Results and conclusion

It was seen that presence or absence of choline peak correlates very well with presence or absence of malignant foci with in the nodule (sensitivity=100%; specificity=88.88%). These results indicate that magnetic resonance spectroscopy may prove to be an useful diagnostic modality for carcinoma thyroid.

Keywords: Magnetic resonance spectroscopy (MRS), Thyroid carcinoma, Choline

To access this article, please choose from the options below

Login to an existing account or Register a new account.

  • Purchase this article for 31.50 USD (You must login/register to purchase this article)

    Online access for 24 hours. The PDF version can be downloaded as your permanent record.

  • Subscribe to this title

    Get unlimited online access to this article and all other articles in this title 24/7 for one year.

  • Claim access now

    For current subscribers with Society Membership or Account Number.

  • Visit SciVerse ScienceDirect to see if you have access via your institution.
 

PII: S0720-048X(07)00141-6

doi:10.1016/j.ejrad.2007.03.006

European Journal of Radiology
Volume 64, Issue 3 , Pages 414-418, December 2007

Article Tools

* Image Usage & Resolution