European Journal of Radiology
Volume 63, Issue 1 , Pages 110-119 , July 2007

Contrast enhanced cartilage imaging: Comparison of ionic and non-ionic contrast agents

  • Edzard Wiener

      Affiliations

    • Department of Radiology, Technical University Munich, Ismaninger Str. 22, D-81675 Munich, Germany
    • Corresponding Author InformationCorresponding author. Tel.: +49 89 4140 2979; fax: +49 89 4140 483.
    • ,
  • Klaus Woertler

      Affiliations

    • Department of Radiology, Technical University Munich, Ismaninger Str. 22, D-81675 Munich, Germany
    • ,
  • Gregor Weirich

      Affiliations

    • Institute of Pathology, Technical University Munich, Troger Str. 18, D-81675 Munich, Germany
    • ,
  • Ernst J. Rummeny

      Affiliations

    • Department of Radiology, Technical University Munich, Ismaninger Str. 22, D-81675 Munich, Germany
    • ,
  • Marcus Settles

      Affiliations

    • Department of Radiology, Technical University Munich, Ismaninger Str. 22, D-81675 Munich, Germany

Received 9 October 2006 ,Revised 14 January 2007 ,Accepted 18 January 2007.

References 

  1. Imhof H, Nobauer-Huhmann IM, Krestan C, et al. MRI of the cartilage. Eur Radiol. 2002;12(11):2781–2793
  2. Foster JE, Maciewicz RA, Taberner J, et al. Structural periodicity in human articular cartilage: comparison between magnetic resonance imaging and histological findings. Osteoarthritis Cartilage. 1999;7(5):480–485
  3. Goodwin DW, Zhu H, Dunn JF. In vitro MR imaging of hyaline cartilage: correlation with scanning electron microscopy. AJR Am J Roentgenol. 2000;174(2):405–409
  4. Xia Y, Moody JB, Burton-Wurster N, Lust G. Quantitative in situ correlation between microscopic MRI and polarized light microscopy studies of articular cartilage. Osteoarthritis Cartilage. 2001;9(5):393–406
  5. Waldschmidt JG, Rilling RJ, Kajdacsy-Balla AA, Boynton MD, Erickson SJ. In vitro and in vivo MR imaging of hyaline cartilage: zonal anatomy, imaging pitfalls, and pathologic conditions. Radiographics. 1997;17(6):1387–1402
  6. Nieminen MT, Rieppo J, Toyras J, et al. T2 relaxation reveals spatial collagen architecture in articular cartilage: a comparative quantitative MRI and polarized light microscopic study. Magn Reson Med. 2001;46(3):487–493
  7. Calvo E, Palacios I, Delgado E, et al. High-resolution MRI detects cartilage swelling at the early stages of experimental osteoarthritis. Osteoarthritis Cartilage. 2001;9(5):463–472
  8. Dunn TC, Lu Y, Jin H, Ries MD, Majumdar S. T2 relaxation time of cartilage at MR imaging: comparison with severity of knee osteoarthritis. Radiology. 2004;232(2):592–598
  9. Paul PK, O’Byrne E, Blancuzzi V, et al. Magnetic resonance imaging reflects cartilage proteoglycan degradation in the rabbit knee. Skeletal Radiol. 1991;20(1):31–36
  10. Bashir A, Gray ML, Boutin RD, Burstein D. Glycosaminoglycan in articular cartilage: in vivo assessment with delayed Gd(DTPA)(2-)-enhanced MR imaging. Radiology. 1997;205(2):551–558
  11. Bashir A, Gray ML, Burstein D. Gd-DTPA2- as a measure of cartilage degradation. Magn Reson Med. 1996;36(5):665–673
  12. Trattnig S, Mlynarik V, Breitenseher M, et al. MRI visualization of proteoglycan depletion in articular cartilage via intravenous administration of Gd-DTPA. Magn Reson Imaging. 1999;17(4):577–583
  13. Tiderius CJ, Olsson LE, Leander P, Ekberg O, Dahlberg L. Delayed gadolinium-enhanced MRI of cartilage (dGEMRIC) in early knee osteoarthritis. Magn Reson Med. 2003;49(3):488–492
  14. Woertler K, Buerger H, Moeller J, Rummeny EJ. Patellar articular cartilage lesions: in vitro MR imaging evaluation after placement in gadopentetate dimeglumine solution. Radiology. 2004;230(3):768–773
  15. Burstein D, Bashir A, Gray ML. MRI techniques in early stages of cartilage disease. Invest Radiol. 2000;35(10):622–638
  16. Schmid MR, Notzli HP, Zanetti M, Wyss TF, Hodler J. Cartilage lesions in the hip: diagnostic effectiveness of MR arthrography. Radiology. 2003;226(2):382–386
  17. Kassarjian A, Yoon LS, Belzile E, Connolly SA, Millis MB, Palmer WE. Triad of MR arthrographic findings in patients with cam-type femoroacetabular impingement. Radiology. 2005;236(2):588–592
  18. Guntern DV, Pfirrmann CW, Schmid MR, et al. Articular cartilage lesions of the glenohumeral joint: diagnostic effectiveness of MR arthrography and prevalence in patients with subacromial impingement syndrome. Radiology. 2003;226(1):165–170
  19. Brandt KD, Smith GN, Simon LS. Intraarticular injection of hyaluronan as treatment for knee osteoarthritis: what is the evidence?. Arthritis Rheum. 2000;43(6):1192–1203
  20. Fragonas E, Mlynarik V, Jellus V, et al. Correlation between biochemical composition and magnetic resonance appearance of articular cartilage. Osteoarthritis Cartilage. 1998;6(1):24–32
  21. Frank LR, Wong EC, Luh WM, Ahn JM, Resnick D. Articular cartilage in the knee: mapping of the physiologic parameters at MR imaging with a local gradient coil—preliminary results. Radiology. 1999;210(1):241–246
  22. Nieminen MT, Toyras J, Laasanen MS, Silvennoinen J, Helminen HJ, Jurvelin JS. Prediction of biomechanical properties of articular cartilage with quantitative magnetic resonance imaging. J Biomech. 2004;37(3):321–328
  23. Wayne JS, Kraft KA, Shields KJ, Yin C, Owen JR, Disler DG. MR imaging of normal and matrix-depleted cartilage: correlation with biomechanical function and biochemical composition. Radiology. 2003;228(2):493–499
  24. Bashir A, Gray ML, Hartke J, Burstein D. Nondestructive imaging of human cartilage glycosaminoglycan concentration by MRI. Magn Reson Med. 1999;41(5):857–865
  25. Tiderius CJ, Svensson J, Leander P, Ola T, Dahlberg L. dGEMRIC (delayed gadolinium-enhanced MRI of cartilage) indicates adaptive capacity of human knee cartilage. Magn Reson Med. 2004;51(2):286–290
  26. Nieminen MT, Menezes NM, Williams A, Burstein D. T2 of articular cartilage in the presence of Gd-DTPA2. Magn Reson Med. 2004;51(6):1147–1152
  27. Kusaka Y, Grunder W, Rumpel H, Dannhauer KH, Gersonde K. MR microimaging of articular cartilage and contrast enhancement by manganese ions. Magn Reson Med. 1992;24(1):137–148
  28. Wachsmuth LR, Raiss RX, Juretschke HP, Schneider JE, Belz U, Metterich K. Magic-angle dependency and Mn2+-diffussion studies to define the biochemical status of articular cartilage. Book of abstract: Fourth Scientific Meeting and Exhibition of the International Society for Magnetic Resonance in Medicine, vol. 2. New York, NY: SMR; 1996. p. 837.
  29. Gillis A, Gray M, Burstein D. Relaxivity and diffusion of gadolinium agents in cartilage. Magn Reson Med. 2002;48(6):1068–1071
  30. Xia Y. Heterogeneity of cartilage laminae in MR imaging. J Magn Reson Imaging. 2000;11(6):686–693
  31. Goodwin DW, Wadghiri YZ, Zhu H, Vinton CJ, Smith ED, Dunn JF. Macroscopic structure of articular cartilage of the tibial plateau: influence of a characteristic matrix architecture on MRI appearance. AJR Am J Roentgenol. 2004;182(2):311–318
  32. Schulte-Altedorneburg G, Gebhard M, Wohlgemuth WA, et al. MR arthrography: pharmacology, efficacy and safety in clinical trials. Skeletal Radiol. 2003;32(1):1–12
  33. Steinbach LS, Palmer WE, Schweitzer ME. Special focus session. MR arthrography. Radiographics. 2002;22(5):1223–1246
  34. Sahin G, Demirtas M. An overview of MR arthrography with emphasis on the current technique and applicational hints and tips. Eur J Radiol. 2006;58(3):416–430
  35. McCauley TR. MR imaging evaluation of the postoperative knee. Radiology. 2005;234(1):53–61
  36. Grainger AJ, Elliott JM, Campbell RS, Tirman PF, Steinbach LS, Genant HK. Direct MR arthrography: a review of current use. Clin Radiol. 2000;55(3):163–176
  37. Elentuck D, Palmer WE. Direct magnetic resonance arthrography. Eur Radiol. 2004;14(11):1956–1967
  38. In den Kleef JJE, Cuppen JJM. RLSQ: T1, T2 and Rho calculations combining ratios and least squares. Magn Reson Med. 1987;5:513–524
  39. Gudbjartsson H, Patz S. The Rician distribution of noisy MRI data. Magn Reson Med. 1995;34(6):910–914
  40. Maier CF, Tan SG, Hariharan H, Potter GH. T2 quantification of articular cartilage at 1.5T. J Magn Reson Imaging. 2003;17:358–364
  41. Smith HE, Mosher TJ, Dardzinski BJ, et al. Spatioal variation in cartilage T2 of the knee. J Magn Reson Imaging. 2001;14:50–55
  42. Poon CS, Henkelman RM. Practical T2 quantitation for clinical applications. J Magn Reson Imaging. 1992;2:541–553
  43. Lee JN, Riederer SJ. A modified saturation-recovery approximation for multiple spin-echo pulse sequences. Magn Reson Med. 1986;3:132–134
  44. Rinck PA, Muller RN. Field strength and dose dependence of contrast enhancement by gadolinium-based MR contrast agents. Eur Radiol. 1999;9(5):998–1004
  45. Reichenbach JR, Hacklander T, Harth T, Hofer M, Rassek M, Modder U. 1H T1 and T2 measurements of the MR imaging contrast agents Gd-DTPA and Gd-DTPA BMA at 1.5T.. Eur Radiol. 1997;7(2):264–274
  46. Hajek PC, Sartoris DJ, Neumann CH, Resnick D. Potential contrast agents for MR arthrography: in vitro evaluation and practical observations. AJR Am J Roentgenol. 1987;149(1):97–104
  47. Maroudas A, Bayliss MT, Venn MF. Further studies on the composition of human femoral head cartilage. Ann Rheum Dis. 1980;39:514–523
  48. Dardzinski BJ, Mosher TJ, Li S, Van Slyke MA, Smith MB. Spatial variation of T2 in human articular cartilage. Radiology. 1997;205(2):546–550
  49. Mosher TJ, Dardzinski BJ, Smith MB. Human articular cartilage: influence of aging and early symptomatic degeneration on the spatial variation of T2-preliminary findings at 3T. Radiology. 2000;214(1):259–266
  50. Borthakur A, Shapiro EM, Beers J, Kudchodkar S, Kneeland JB, Reddy R. Sensitivity of MRI to proteoglycan depletion in cartilage: comparison of sodium and proton MRI. Osteoarthritis Cartilage. 2000;8(4):288–293
  51. Stanisz GJ, Henkelman RM. Gd-DTPA relaxivity depends on macromolecular content. Magn Reson Med. 2000;44(5):665–667

PII: S0720-048X(07)00033-2

doi: 10.1016/j.ejrad.2007.01.019

European Journal of Radiology
Volume 63, Issue 1 , Pages 110-119 , July 2007

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