European Journal of Radiology
Volume 50, Issue 2 , Pages 177-200 , May 2004

Imaging in spine and spinal cord malformations

  • Andrea Rossi

      Affiliations

    • Department of Neuroradiology, G. Gaslini Children’s Research Hospital, Largo G. Gaslini 5, I-16147 Genova, Italy
    • Corresponding Author InformationCorresponding author. Tel.: +39-010-5636516; fax: +39-010-3779798.
    • ,
  • Roberta Biancheri

      Affiliations

    • Department of Neuroradiology, G. Gaslini Children’s Research Hospital, Largo G. Gaslini 5, I-16147 Genova, Italy
    • ,
  • Armando Cama

      Affiliations

    • Department of Neurosurgery, G. Gaslini Children’s Research Hospital, Largo G. Gaslini 5, I-16147 Genova, Italy
    • ,
  • Gianluca Piatelli

      Affiliations

    • Department of Neurosurgery, G. Gaslini Children’s Research Hospital, Largo G. Gaslini 5, I-16147 Genova, Italy
    • ,
  • Marcello Ravegnani

      Affiliations

    • Department of Neurosurgery, G. Gaslini Children’s Research Hospital, Largo G. Gaslini 5, I-16147 Genova, Italy
    • ,
  • Paolo Tortori-Donati

      Affiliations

    • Department of Neuroradiology, G. Gaslini Children’s Research Hospital, Largo G. Gaslini 5, I-16147 Genova, Italy

Received 3 October 2003 ,Revised 9 October 2003 ,Accepted 13 October 2003.

References 

  1. Tortori-Donati P, Rossi A, Cama A. Spinal dysraphism: a review of neuroradiological features with embryological correlations and proposal for a new classification. Neuroradiology. 2000;42:471–491
  2. Tortori-Donati P, Rossi A, Biancheri R, Cama A. Magnetic resonance imaging of spinal dysraphism. Top. Magn. Reson. Imaging. 2001;12:375–409
  3. Naidich TP, Blaser SI, Delman BN, McLone DG, Dias MS, Zimmerman RA, et al. Embryology of the spine and spinal cord. Proceedings of ASNR 2002 Congress, p. 3–13.
  4. Nievelstein RAJ, Hartwig NG, Vermeji-Keers C, Valk J. Embryonic development of the mammalian caudal neural tube. Teratology. 1993;48:21–31
  5. Catala M. Genetic control of caudal development. Clin. Genet. 2002;61:89–96
  6. Warder DE. Tethered cord syndrome and occult spinal dysraphism. Neurosurg Focus [serial online] January 2001;10:Article 1. Available at http://www.neurosurgery.org/focus/jan01/10-1-1.pdf. Accessed 20 November 2001.
  7. Drolet B. Birthmarks to worry about. Cutaneous markers of dysraphism. Dermatol. Clin. 1998;16:447–453
  8. French BN. The embryology of spinal dysraphism. Clin. Neurosurg. 1983;30:295–340
  9. Sattar MT, Bannister CM, Turnbull IW. Occult spinal dysraphism—The common combination of lesions and the clinical manifestations in 50 patients. Eur. J Pediatr. Surg. 1996;6(Supple I):10–14
  10. Warder DE, Oakes WJ. Tethered cord syndrome and the conus in a normal position. Neurosurgery. 1993;33:374–378
  11. Warder DE, Oakes WJ. Tethered cord syndrome: the low-lying and normally positioned conus. Neurosurgery. 1994;34:597–600
  12. Herman JM, McLone DG, Storrs BB, Dauser RC. Analysis of 153 patients with myelomeningocele or spinal lipoma reoperated upon for a tethered cord. Pediatr. Neurosurg. 1993;19:243–249
  13. McLone DG, Dias MS. Complications of myelomeningocele closure. Pediatr. Neurosurg. 1991-92;17:267–273
  14. Scott RM, Wolpert SM, Bartoshesky LF, Zimbler S, Klauber GT. Dermoid tumors occurring at the site of previous myelomeningocele repair. J Neurosurg. 1986;65:779–783
  15. Tortori-Donati P, Cama A, Fondelli MP, Rossi A. Le malformazioni di Chiari. In: Tortori-Donati P, Taccone A, Longo M. (Eds.), Malformazioni cranio-encefaliche. Neuroradiologia. Turin: Minerva Medica 1996. p. 209–36.
  16. Pang D, Dias MS, Ahab-Barmada M. Split cord malformation, Part I: A unified theory of embryogenesis for double spinal cord malformations. Neurosurgery. 1992;31:451–480
  17. Breningstall GN, Marker SM, Tubman DE. Hydrosyringomyelia and diastematomyelia detected by MRI in myelomeningocele. Pediatr. Neurol. 1992;8:267–271
  18. Pang D. Split cord malformation. Part II: Clinical syndrome. Neurosurgery. 1992;31:481–500
  19. Cama A, Tortori-Donati P, Piatelli GL, Fondelli MP, Andreussi L. Chiari complex in children. Neuroradiological diagnosis, neurosurgical treatment and proposal of a new classification (312 cases). Eur. J Pediatr. Surg. 1995;5(Suppl 1):35–38
  20. McLone DG, Knepper PA. The cause of Chiari II malformation: a unified theory. Pediatr Neurosci. 1989;15:1–12
  21. Naidich TP, McLone DG, Fulling F. The Chiari II malformation. Part IV. The hindbrain deformity. Neuroradiology. 1983;25:179–197
  22. Naidich TP, McLone DG, Mutleur S. A new understanding of dorsal dysraphism with lipoma (lipomyeloschisis): radiological evaluation and surgical correction. AJNR Am. J Neuroradiol. 1983;4:103–116
  23. Pierre-Kahn A, Zerah M, Renier D, Cinalli G, Sainte-Rose C, Lellouch-Tubiana A, et al.  Congenital lumbosacral lipomas. Childs Nerv. Syst. 1997;13:298–334
  24. Knittle JL, Timmers K, Ginsberg-Fellner F, Brown RE, Katz DP. The growth of adipose tissue in children and adolescents. Cross-sectional and longitudinal studies of adipose cell number and size. J Clin. Invest. 1979;63:246–269
  25. Catala M. Embryogenesis. Why do we need a new explanation for the emergence of spina bifida with lipoma?. Childs Nerv. Syst. 1997;13:336–340
  26. Lee KS, Gower DJ, McWhorter JM, Albertson DA. The role of MR imaging in the diagnosis and treatment of anterior sacral meningocele. Report of 2 cases. J Neurosurg. 1988;69:628–631
  27. Byrd SE, Harvey C, Darling CF. MR of terminal myelocystoceles. Eur. J Radiol. 1995;20:215–220
  28. McLone DG, Naidich TP. Terminal myelocystocele. Neurosurgery. 1985;16:36–43
  29. Peacock WJ, Murovic JA. Magnetic resonance imaging in myelocystoceles. Report of two cases. J Neurosurg. 1989;70:804–807
  30. Carey JC, Greenbaum B, Hall BD. The OEIS complex (omphalocele, exstrophy, imperforate anus, spinal defects). Birth Defects Orig. Artic. Ser. 1978;14:253–263
  31. Smith NM, Chambers HM, Furness ME, Haan EA. The OEIS complex omphalocele-exstrophy-imperforate anus-spinal defects: recurrence in sibs. J Med. Genet. 1992;29:730–732
  32. Tortori-Donati P, Cama A, Rosa ML, Andreussi L, Taccone A. Occult spinal dysraphism: neuroradiological study. Neuroradiology. 1990;31:512–522
  33. Raghavan N, Barkovich AJ, Edwards M, Norman D. MR imaging in the tethered spinal cord syndrome. AJNR Am J Neuroradiol. 1989;10:27–36
  34. Brown E, Matthes JC, Bazan C, Jinkins JR. Prevalence of incidental intraspinal lipoma of the lumbosacral spine as determined by MRI. Spine. 1994;19:833–836
  35. Uchino A, Mori T, Ohno M. Thickened fatty filum terminale: MR imaging. Neuroradiology. 1991;33:331–333
  36. Yundt KD, Park TS, Kaufman BA. Normal diameter of filum terminale in children: in vivo measurement. Pediatr Neurosurg. 1997;27:257–259
  37. Scotti G, Harwood-Nash DC. Congenital thoracic dermal sinus: diagnosis by computer assisted metrizamide myelography. J Comput. Assist. Tomogr. 1980;4:675–677
  38. Barkovich AJ, Edwards MSB, Cogen PH. MR evaluation of spinal dermal sinus tracts in children. AJNR Am J Neuroradiol. 1991;12:123–129
  39. Weprin BE, Oakes WJ. Coccygeal pits. Pediatrics. 2000;105:E69
  40. Elton S, Oakes WJ. Dermal sinus tracts of the spine. Neurosurg Focus [serial online]. January 2001;10:Article 4. Available at: http://www.neurosurgery.org/focus/jan01/10-1-4.pdf Accessed 22 May 2003.
  41. Kernohan JW. The ventriculus terminalis: its growth and development. J Comp. Neurol. 1924;38:10–125
  42. Coleman LT, Zimmerman RA, Rorke LB. Ventriculus terminalis of the conus medullaris: MR findings in children. AJNR Am. J Neuroradiol. 1995;16:1421–1426
  43. Sigal R, Denys A, Halimi P, Shapeero L, Doyon D, Boudghène F. Ventriculus terminalis of the conus medullaris: MR imaging in four patients with congenital dilatation. AJNR Am J Neuroradiol. 1991;12:733–737
  44. Dias MS, Walker ML. The embryogenesis of complex dysraphic malformations: a disorder of gastrulation?. Pediatr. Neurosurg. 1992;18:229–253
  45. Prop N, Frensdorf EL. A postvertebral endodermal cyst associated with axial deformities: a case showing the “endodermal–ectodermal adhesion syndrome”. Pediatrics. 1967;39:555–562
  46. Faris JC, Crowe JE. The split notochord syndrome. J Pediatr. Surg. 1975;10:467–472
  47. Naidich TP, Harwood-Nash DC. Diastematomyelia. Part I. Hemicords and meningeal sheaths. Single and double arachnoid and dural tubes. AJNR Am J Neuroradiol. 1983;4:633–636
  48. Schlesinger AE, Naidich TP, Quencer RM. Concurrent hydromyelia and diastematomyelia. AJNR Am J Neuroradiol. 1986;7:473–477
  49. Tortori-Donati P, Fondelli MP, Rossi A. Anomalie congenite del midollo spinale. In: Simonetti G, Del Maschio A, Bartolozzi C, Passariello R, editors. Trattato Italiano di Risonanza Magnetica. Naples: Idelson-Gnocchi; 1998. p. 517–53.
  50. Tortori-Donati P, Fondelli MP, Rossi A, Raybaud CA, Cama A, Capra V. Segmental spinal dysgenesis. Neuroradiologic findings with clinical and embryologic correlation. AJNR Am J Neuroradiol. 1999;20:445–456
  51. Duhamel B. From the mermaid to anal imperforation: the syndrome of caudal regression. Arch. Dis. Child. 1961;36:152–155
  52. Currarino G, Coln D, Votteler T. Triad of anorectal, sacral, and presacral anomalies. AJR Am J Roentgenol. 1981;137:395–398
  53. Dias MS, Azizkhan RG. A novel embryogenetic mechanism for Currarino’s triad: inadequate dorsoventral separation of the caudal eminence from hindgut endoderm. Pediatr. Neurosurg. 1998;28:223–229
  54. Gudinchet F, Maeder P, Laurent T, Meyrat B, Schnyder P. Magnetic resonance detection of myelodysplasia in children with Currarino triad. Pediatr. Radiol. 1997;27:903–907
  55. Pang D. Sacral agenesis and caudal spinal cord malformations. Neurosurgery. 1993;32:755–779
  56. Nievelstein RAJ, Valk J, Smit LME, Vermeji-Keers C. MR of the caudal regression syndrome: embryologic implications. AJNR Am J Neuroradiol. 1994;15:1021–1029
  57. Barkovich AJ, Raghavan N, Chuang SH. MR of lumbosacral agenesis. AJNR Am J Neuroradiol. 1989;10:1223–1231

PII: S0720-048X(03)00312-7

doi: 10.1016/j.ejrad.2003.10.015

European Journal of Radiology
Volume 50, Issue 2 , Pages 177-200 , May 2004

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