Foci of decreased signal on T2-weighted MR images in leiomyosarcomas of soft tissue: correlation between MR and histological findings

Pilavaki, M; Drevelegas, A; Nenopoulou, H; Scordalaki, A; Chourmouzi, D; Sofroniadis, I; Dimitriadis, A.S

doi:10.1016/j.ejrad.2003.10.008

« Previous Next »European Journal of Radiology
Volume 51, Issue 3 , Pages 279-285, September 2004

Foci of decreased signal on T2-weighted MR images in leiomyosarcomas of soft tissue: correlation between MR and histological findings

M Pilavaki
- Department of Radiology, General Hospital “G. Papanikolaou”, Exohi 57010, Thessaloniki, Greece
- Corresponding author. Tel.: +32-31-459645; fax: +32-31-350610.
A Drevelegas
- Department of Radiology, School of Medicine, Ahepa Hospital, Aristotle University of Thessaloniki, Thessaloniki, Greece
H Nenopoulou
- Department of Pathology, School of Medicine, Aristotle University of Thessaloniki, Thessaloniki, Greece
A Scordalaki
- Laboratory of Pathology, General Hospital “G. Papanikolaou”, Thessaloniki, Greece
D Chourmouzi
- Interbalcan Medical Center, Thessaloniki, Greece
I Sofroniadis
- Department of Radiation Oncology, School of Medicine, Ahepa Hospital, Aristotle University of Thessaloniki, Thessaloniki, Greece
A.S Dimitriadis
- Department of Radiology, School of Medicine, Ahepa Hospital, Aristotle University of Thessaloniki, Thessaloniki, Greece

Received 23 June 2003; received in revised form 7 October 2003; accepted 9 October 2003.

Abstract

Objective: Leiomyosarcomas are rare soft tissue sarcomas with varying MR signal characteristics and histologic pictures. The purpose of this study was to investigate the histological features of foci, which showed decreased signal on T2-weighted images in leiomyosarcomas of soft tissue. Material and methods: We reviewed the MR images of six histologically proved cases of leiomyosarcomas of soft tissue and correlated the foci, which showed decreased signal on T2-weighted images with the histologic findings. Result: Microscopic examination revealed that these foci were composed of hyalinization of neoplastic tissue, internal septations, deposition of hemosiderin, or corresponded to metaplastic bone. Conclusion: The authors explain that the foci of decreased signal on T2-weighted MR images correspond to tissue components of the lesion, particularly fibrous tissue, hemosiderin and metaplastic bone. So, the suggestion is that leiomyosarcoma should be considered in the differential diagnosis of soft-tissue tumors that show foci of decreased signal on T2-weighted MR images.

Keywords: Leiomyosarcoma, Soft tissue tumors, Tissue characterization, MRI