European Journal of Radiology
Volume 51, Issue 3 , Pages 195-201 , September 2004

MRI measurements of water diffusion: impact of region of interest selection on ischemic quantification

  • Yelda Ozsunar

      Affiliations

    • Department of Radiology, School of Medicine, Adnan Menderes University, Aydin 09100, Turkey
    • Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Boston, USA
    • Corresponding Author InformationCorresponding author. Tel.: +90-256-212-0020-333; fax: +90-256-212-01-46.
    • ,
  • Kutsi Koseoglu

      Affiliations

    • Department of Radiology, School of Medicine, Adnan Menderes University, Aydin 09100, Turkey
    • ,
  • Thierry A.G.M Huisman

      Affiliations

    • Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Boston, USA
    • ,
  • Walter Koroshetz

      Affiliations

    • Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston, USA
    • ,
  • A.Gregory Sorensen

      Affiliations

    • Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Boston, USA

Received 18 June 2003 ,Revised 19 September 2003 ,Accepted 22 September 2003.

References 

  1. Moseley ME, Kucharczyk J, Mintorovitch J, Cohen Y, Kurhanewicz J, Derugin N, et al.  Diffusion-weighted MR imaging of acute stroke: correlation with T2-weighted and magnetic susceptibility-enhanced MR imaging in cats. AJNR Am. J. Neuroradiol. 1990;11:423–429
  2. Moseley ME, Vexler Z, Asgari HS, Mintorovitch J, Derugin N, Rocklage S. Comparison of Gd- and Dy-chelates for T2 contrast-enhanced imaging. Magn. Reson. Med. 1991;22:259–267
  3. Darby DG, Barber PA, Gerraty RP, Desmond PM, Yang Q, Parsons M, et al.  Pathophysiological topography of acute ischemia by combined diffusion-weighted and perfusion MRI. Stroke. 1999;30:2043–2052
  4. Lecouvet FE, Duprez TP, Raymackers JM, Peeters A, Cosnard G. Resolution of early diffusion-weighted and FLAIR MRI abnormalities in a patient with TIA. Neurology. 1999;52:1085–1087
  5. Pierpaoli C, Jezzard P, Basser PJ, Barnett A, Di Chiro G. Diffusion tensor MR imaging of the human brain. Radiology. 1996;20:637–648
  6. Sorensen AG, Wu O, Copen WA, Davis TL, Gonzalez RG, Koroshetz WJ, et al.  Human acute cerebral ischemia: detection of changes in water diffusion anisotropy by using MR imaging. Radiology. 1999;212:785–792
  7. Tong DC, Adami A, Moseley ME, Marks MP. Relationship between apparent diffusion coefficient and subsequent hemorrhagic transformation following acute ischemic stroke. Stroke. 2000;31:2378–2384
  8. Selim M, Fink JN, Kumar S, Caplan LR, Horkan C, Chen Y, et al  Predictors of hemorrhagic transformation after intravenous recombinant tissue plasminogen activator: prognostic value of the initial apparent diffusion coefficient and diffusion-weighted lesion volume. Stroke. 2002;33(8):2047–2052
  9. Pierpaoli C, Alger JR, Righini A, Mattiello J, Dickerson R, Des Pres D, et al.  High temporal resolution diffusion MRI of global cerebral ischemia and reperfusion. J. Cereb. Blood Flow Metab. 1996;16:892–905
  10. Schlaug G, Benfield A, Baird AE, Siewert B, Lovblad KO, Parker RA, et al.  The ischemic penumbra: operationally defined by diffusion and perfusion MRI. Neurology. 1999;22(53):1528–1537
  11. Neumann-Haefelin T, Wittsack HJ, Wenserski F, Li TQ, Moseley ME, et al.  Diffusion- and perfusion-weighted MRI. The DWI/PWI mismatch region in acute stroke. Stroke. 1999;30:1591–1597
  12. Karonen JO, Vanninen RL, Liu Y, Ostergaard L, Kuikka JT, Nuutinen J, et al.  Combined diffusion and perfusion MRI with correlation to single-photon emission CT in acute ischemic stroke. Ischemic penumbra predicts infarct growth. Stroke. 1999;30:1583–1590
  13. Rother J, de Crespigny AJ, D’Arceuil H, Iwai K, Moseley ME. Recovery of apparent diffusion coefficient after ischemia-induced spreading depression relates to cerebral perfusion gradient. Stroke. 1996;27:980–987
  14. Dijkhuizen RM, Berkelbach van der Sprenkel JW, Tulleken KA, Nicolay K. Regional assessment of tissue oxygenation and the temporal evolution of hemodynamic parameters and water diffusion during acute focal ischemia in rat brain. Brain Res. 1997;7(750):161–170
  15. Kajima T, Azuma K, Itoh K, Kagawa R, Yamane K, Okada Y, et al.  Diffusion anisotropy of cerebral ischaemia. Acta Neurochir. Suppl. (Wien). 1994;60:216–219
  16. Hoehn-Berlage M, Eis M, Back T, Kohno K, Yamashita K. Changes of relaxation times (T1, T2) and apparent diffusion coefficient after permanent middle cerebral artery occlusion in the rat: temporal evolution, regional extent, and comparison with histology. Magn. Reson. Med. 1995;34:824–834
  17. Pierpaoli C, Righini A, Linfante I, Tao-Cheng JH, Alger JR, Di Chiro G. Histopathologic correlates of abnormal water diffusion in cerebral ischemia: diffusion-weighted MR imaging and light and electron microscopic study. Radiology. 1993;189:439–448
  18. Sorensen AG, Copen WA, Ostergaard L, Buonanno FS, Gonzalez RG, Rordorf G, et al.  Hyperacute stroke: simultaneous measurement of relative cerebral blood volume, relative cerebral blood flow, and mean tissue transit time. Radiology. 1999;210:519–527
  19. Dardzinski BJ, Sotak CH, Fisher M, Hasegawa Y, Li L, Minematsu K. Apparent diffusion coefficient mapping of experimental focal cerebral ischemia using diffusion-weighted echo-planar imaging. Magn. Reson. Med. 1993;30:318–325
  20. Bernarding J, Braun J, Hohmann J, Mansmann U, Hoehn-Berlage M, et al.  Histogram-based characterization of healthy and ischemic brain tissues using multiparametric MR imaging including apparent diffusion coefficient maps and relaxometry. Magn. Reson. Med. 2000;43:52–61
  21. Pierce AR, Lo EH, Mandeville JB, Gonzalez RG, Rosen BR, Wolf GL. MRI measurements of water diffusion and cerebral perfusion: their relationship in a rat model of focal cerebral ischemia. J. Cereb. Blood Flow Metab. 1997;17:183–190
  22. Welch KM, Windham J, Knight RA, Nagesh V, Hugg JW, Jacobs M, et al.  A model to predict the histopathology of human stroke using diffusion and T2-weighted magnetic resonance imaging. Stroke. 1995;26:1983–1989
  23. Yang Q, Tress BM, Barber PA, Desmond PM, Darby DG, Gerraty RP, et al  Serial study of apparent diffusion coefficient and anisotropy in patients with acute stroke. Stroke. 1999;30:2382–2390
  24. Zelaya F, Flood N, Chalk JB, Wang D, Doddrell DM, Strugnell W, et al.  An evaluation of the time dependence of the anisotropy of the water diffusion tensor in acute human ischemia. Magn. Reson. Imaging. 1999;17:331–348
  25. Armitage PA, Bastin ME, Marshall I, Wardlaw JM, Cannon J. Diffusion anisotropy measurements in ischaemic stroke of the human brain. MAGMA. 1998;6(1):28–36
  26. Basser PJ, Mattiello J, Le Bihan D. MR diffusion tensor spectroscopy and imaging. Biophys. J. 1994;66:259–267
  27. Basser PJ, Mattiello J, Le Bihan D. Estimation of the effective self-diffusion tensor from the NMR spin echo. J. Magn. Reson. Imaging. 1994;103:247–254
  28. Mattiello J, Basser PJ, Le Bihan D. The b matrix in diffusion tensor echo-planar imaging. Magn. Reson. Med. 1997;37:292–300
  29. Baird AE, Warach S. Magnetic resonance imaging of acute stroke. J. Cereb. Blood Flow Metab. 1998;18:583–609
  30. Rowley HA, Grant PE, Roberts TP. Diffusion MR imaging. Theory and applications. Neuroimaging Clin. North Am. 1999;9:343–361
  31. Provenzale JM, Sorensen AG. Diffusion-weighted MR imaging in acute stroke: theoretic considerations and clinical applications. AJR. 1999;173:1459–1467
  32. Yasargil MG. Microneurosurgery, vol. IV. New York: Thieme; 1994. p. 28–31.
  33. Hoehn-Berlage M, Norris DG, Kohno K, Mies G, Leibfritz D, Hossmann KA. Evolution of regional changes in apparent diffusion coefficient during focal ischemia of rat brain: the relationship of quantitative diffusion NMR imaging to reduction in cerebral blood flow and metabolic disturbances. J. Cereb. Blood Flow Metab. 1995;15:1002–1011
  34. Park CK, Nehls DG, Graham DI, Teasdale GM, McCulloch J. The glutamate antagonist MK-801 reduces focal ischemic brain damage in the rat. Ann. Neurol. 1988;24:543–551
  35. Mussurakis S, Buckley DL, Drew PJ, Fox JN, Carleton PJ, Turnbull LW. Horsman A Dynamic MR imaging of the breast combined with analysis of contrast agent kinetics in the differentiation of primary breast tumours. Clin. Radiol. 1997;52:516–526
  36. Aronen HJ, Gazit IE, Louis DN, Buchbinder BR, Pardo FS, Weisskoff RM, et al.  Cerebral blood volume maps of gliomas: comparison with tumor grade and histologic findings. Radiology. 1994;191:41–51
  37. Gribbestad IS, Nilsen G, Fjosne HE, Kvinnsland S, Haugen OA, Rinck PA. Comparative signal intensity measurements in dynamic gadolinium-enhanced MR mammography. J. Magn. Reson. Imaging. 1994;4:477–480
  38. Lev MH, Kulke SF, Sorensen AG, Boxerman JL, Brady TJ, Rosen BR, et al.  Contrast-to-noise ratio in functional MRI of relative cerebral blood volume with sprodiamide injection. J. Magn. Reson. Imaging. 1997;7:523–527
  39. Mazziotta JC, Pelizzari CC, Chen GT, Bookstein FL, Valentino D. Region of interest issues: the relationship between structure and function in the brain. J. Cereb. Blood Flow Metab. 1991;11:A51–A56
  40. Constable RT, Skudlarski P, Mencl E, Pugh KR, Fulbright RK, Lacadie C, et al.  Quantifying and comparing region-of-interest activation patterns in functional brain MR imaging: methodology considerations. Magn. Reson. Imaging. 1998;16:289–300

PII: S0720-048X(03)00273-0

doi: 10.1016/j.ejrad.2003.09.013

European Journal of Radiology
Volume 51, Issue 3 , Pages 195-201 , September 2004

Article Tools

* Image Usage & Resolution