Multidetector row CT angiography of the abdominal aorta and lower extremities in patients with peripheral arterial occlusive disease: diagnostic accuracy and interobserver agreement

Romano, Maurizio; Mainenti, Pier Paolo; Imbriaco, Massimo; Amato, Bruno; Markabaoui, Karim; Tamburrini, Oscar; Salvatore, Marco

doi:10.1016/S0720-048X(03)00118-9

Next »European Journal of Radiology
Volume 50, Issue 3 , Pages 303-308, June 2004

Multidetector row CT angiography of the abdominal aorta and lower extremities in patients with peripheral arterial occlusive disease: diagnostic accuracy and interobserver agreement

Maurizio Romano
- Department of Radiology and Radiotherapy, University “Federico II”, 5, Via Pansini, 80131 Naples, Italy
- Institute of Biostructures and Bioimages, National Research Council, 5, Via Pansini, 80131 Naples, Italy
- Corresponding author. Present address: 3, Via Luca da Penne, 80122 Naples, Italy. Tel.: +39-08-1746-3560; fax: +39-08-1545-7081.
Pier Paolo Mainenti
- Department of Radiology and Radiotherapy, University “Federico II”, 5, Via Pansini, 80131 Naples, Italy
- Institute of Biostructures and Bioimages, National Research Council, 5, Via Pansini, 80131 Naples, Italy
Massimo Imbriaco
- Department of Radiology and Radiotherapy, University “Federico II”, 5, Via Pansini, 80131 Naples, Italy
- Institute of Biostructures and Bioimages, National Research Council, 5, Via Pansini, 80131 Naples, Italy
Bruno Amato
- Department of Surgery, University “Federico II”, 5, Via Pansini, 80131 Naples, Italy
Karim Markabaoui
- Department of Surgery, University “Federico II”, 5, Via Pansini, 80131 Naples, Italy
Oscar Tamburrini
- Unit of Radiology, University “Magna Graecia”, Catanzaro, 115, Via T. Campanella, 88100 Catanzaro, Italy
Marco Salvatore
- Department of Radiology and Radiotherapy, University “Federico II”, 5, Via Pansini, 80131 Naples, Italy

Received 30 October 2002; received in revised form 24 March 2003; accepted 26 March 2003.

Abstract

Purpose: To evaluate the accuracy of four channel multidetector row CT angiography (MDCTA) of the abdominal aorta and lower extremities arteries compared with digital subtraction angiography (DSA). Materials and methods: In our prospective study 42 patients with peripheral vascular occlusive disease (27 M, 15 F, age range 40–79 years) underwent MDCTA and DSA within 5 days. Images were blindly interpreted by two radiologists. Maximum intensity projections (MIP), multiplanar (MPR) reformations, three-dimensional (3D) reconstructions as well as axial images were available for analysis of MDCTA. DSA were analyzed on hard copies. Results: Overall sensitivity and specificity of MDCTA were 93 and 95%, respectively, with positive and negative predictive values of 90 and 97%. Overall diagnostic accuracy was 94%. Normal arterial segments and 100% occlusions were correctly identified in all cases by MDCTA. Moderately stenotic segments interpretation in the calves appeared to be more controversial, but no statistical difference in accuracy of MDCTA in the infrapopliteal district arteries was noted with respect to accuracy in the more proximal arterial bed. Good to excellent interobserver and intraobserver agreement were observed, with k values greater than 0.80. Conclusions: MDCTA of the abdominal aorta and lower extremities is an accurate imaging modality in clinical practice when compared with DSA.

Keywords: Computed tomography, Angiography arteries, Extremities angiography, Comparative studies