European Journal of Radiology
Volume 44, Issue 3 , Pages 210-215, December 2002

MR-pathologic correlation of lung specimens

  • Hiroto Hatabu

      Affiliations

    • Department of Radiology, Harvard Medical School, Beth Israel Deaconess Medical Center, 330 Brookline Avenue, Boston, MA 02215, USA
    • Department of Radiology, University of Pennsylvania Medical Center, Philadelphia, PA, USA
    • Corresponding Author InformationCorresponding author. Tel.: +1-617-667-2387; fax: +1-617-667-8212
  • ,
  • Hidemasa Uematsu

      Affiliations

    • Department of Radiology, University of Pennsylvania Medical Center, Philadelphia, PA, USA
    • Department of Radiology, Fukui Medical University, Fukui, Japan
  • ,
  • Ichiro Hasegawa

      Affiliations

    • Department of Radiology, Harvard Medical School, Beth Israel Deaconess Medical Center, 330 Brookline Avenue, Boston, MA 02215, USA
  • ,
  • Harumi Itoh

      Affiliations

    • Department of Radiology, Fukui Medical University, Fukui, Japan

Received 5 September 2002; received in revised form 6 September 2002; accepted 9 September 2002.

Abstract 

The aim of this study was to assess the feasibility of a new MR-pathologic correlation method utilizing a high-resolution MR technique with a 3-inch surface coil and elimination of susceptibility by replacing air in the pulmonary alveoli of lung specimens with water. Inflated cadaver lung specimens of various lung disorders were imaged using a conventional spin echo (SE) sequence in a clinical 1.5T MR scanner. The MR images were correlated with pathologic specimens. In six out of seven specimens, MR revealed detailed images corresponding to pathological changes. MR may provide a non-invasive and non-destructive method for examining lung specimens and for image-pathologic correlation.

Keywords:  Lung, MR, Magnetic resonance imaging, Lung cancer, Pathology, Calcinosis

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PII: S0720-048X(02)00270-X

European Journal of Radiology
Volume 44, Issue 3 , Pages 210-215, December 2002