European Journal of Radiology
Volume 43, Issue 3 , Pages 256-261 , September 2002

Comparative diagnostic value and therapeutic relevance of magnetic resonance imaging and bone marrow scintigraphy in patients with metastatic solid tumors of the axial skeleton

  • Nadir Ghanem

      Affiliations

    • Department of Diagnostic Radiology, University Hospital Freiburg, Hugstetter Strasse 55, 79106 Freiburg, Germany
    • Corresponding Author InformationCorresponding author. Tel.: +49-761-270-3837; fax: +49-761-270-3831
  • ,
  • Carsten Altehoefer

      Affiliations

    • Department of Diagnostic Radiology, University Hospital Freiburg, Hugstetter Strasse 55, 79106 Freiburg, Germany
  • ,
  • Stefan Högerle

      Affiliations

    • Department of Nuclear Medicine, University Hospital Freiburg, Hugstetter Strasse 55, 79106 Freiburg, Germany
  • ,
  • Oliver Schäfer

      Affiliations

    • Department of Diagnostic Radiology, University Hospital Freiburg, Hugstetter Strasse 55, 79106 Freiburg, Germany
  • ,
  • Jan Winterer

      Affiliations

    • Department of Diagnostic Radiology, University Hospital Freiburg, Hugstetter Strasse 55, 79106 Freiburg, Germany
  • ,
  • Ernst Moser

      Affiliations

    • Department of Nuclear Medicine, University Hospital Freiburg, Hugstetter Strasse 55, 79106 Freiburg, Germany
  • ,
  • Mathias Langer

      Affiliations

    • Department of Diagnostic Radiology, University Hospital Freiburg, Hugstetter Strasse 55, 79106 Freiburg, Germany

Received 3 August 2001 ,Revised 26 November 2001 ,Accepted 29 November 2001.

References 

  1. Sherry MM, Greco FA, Johnson DH, Hainsworth ID. Breast cancer with skeletal metastases at initial diagnosis. Distinctive clinical characteristics and favourable prognosis. Cancer. 1986;58:178–182
  2. Schocker JD, Brady LW. Radiation therapy for bone metastasis. Clin. Orthop. Relat. Res. 1982;169:38–43
  3. Gilbert HA, Kagan R, Nussbaum H, Rao AI, Satzman I, Chan P, et al.  Evaluation of radiation therapy for bone metastases: pain relief and quality of life. Am. J. Roentgenol. 1977;129:1095–1096
  4. Rossellini DelTurco M, Palli D, Cariddi A, Ciatto S, Pacini P, Distante V. Intensive diagnostic follow-up after treatment of primary breast cancer: a randomized trial. J. Am. Med. Assoc. 1994;271:1593–1597
  5. Abrams HL, Spiro R, Goldstein N. Metastases in carcinoma: analysis of 1000 autopsied cases. Cancer. 1950;3:336–340
  6. Coleman RE, Rubens RD. Bone metastases and breast cancer. Cancer Treat. Rev. 1985;12:251–270
  7. Kamby C, Vejborg I, Daugaard S, Guldhammer B, Dirksen H, Rossing N, et al.  Clinical and radiological characteristics of bone metastases in breast cancer. Cancer. 1987;60:2524–2531
  8. Wikenheiser KA, Silberstein EB. Bone scintigraphy screening in stage I-II breast cancer: is it cost-effective?. Clevel. Clin. J. Med. 1996;63:43–44
  9. Layer G, Steudel A, Schüller H, van Kaick G, Grünwald F, Reiser M, et al.  MRI to detect bone marrow metastases in the initial staging of small cell lung carcinoma and breast carcinoma. Cancer. 1999;85:1004–1009
  10. Layer G, Rieker O, Dörr D, Schnakenberg D, Steudel A, Reiser M. MRI and bone marrow scintigraphy for screening for bone metastases in patients with carcinoma of the breast. Fortschr. Röntgenstr. 1994;160:448–452
  11. Decho T, Horstmann G, Randzio G. A comparison between BMS and MRI in oncological patients. Fortschr. Röntgenstr. 1991;154:300–305
  12. Ludwig H, Kumpan W, Sinzinger H. Radiography and bone scintigraphy in multiple myeloma: a comparative analysis. Br. J. Radiol. 1983;55:173–181
  13. Mundy GR. Mechanisms of bone metastasis. Cancer. 1997;80:1546–1556
  14. Reske SN. Recent advances in bone marrow scanning. Eur. J. Nucl. Med. 1991;18:203–221
  15. Reske SN, Karstens JH, Glöckner WM, Ammon J, Büll U. Proof of bone marrow involvement in carcinoma of the female breast and in malignant lymphomas via radioimmunoscintigraphy of haematopoietic bone marrow. Fortschr. Röntgenstr. 1990;152:60–66
  16. Altehoefer C, Blum U, Bathmann J, Wüstenberg C, Uhrmeister P, Laubenberger J, et al.  Comparative accuracy of magnetic resonance imaging and immunoscintigraphy for detection of bone marrow involvement in patients with malignant lymphoma. J. Clin. Oncol. 1997;15:1754–1760
  17. Altehoefer C, Ghanem N, Högerle S, Moser E, Langer M. Comparative detectability of bone metastases and impact on therapy of magnetic resonance imaging and bone marrow scintigraphy in patients with breast cancer. Eur. J. Radiol. 2001;40:16–23
  18. Haubold-Reuter B, Duewell S, Schilcher B, Marincek B, von Schulthess GK. Fast spin echo MRI and bone scintigraphy in the detection of skeletal metastases. Eur. J. Radiol. 1993;3:316–320
  19. Vande Berg BC, Malghem J, Lecouvet FE, Maldaque B. Magnetic resonance imaging of the normal bone marrow. Skeletal Radiol. 1998;27:471–483
  20. Flickinger FW, Sanal SM. Bone marrow MRI: techniques and accuracy for detecting breast cancer metastases. Magn. Reson. Imaging. 1994;12:829–835
  21. Eustace S, Tello R, DeCarvalho V, Carey J, Melhem E, Yucel EK. A comparison of whole-body turboSTIR MR imaging and planar 99mTc-methylene diphosphonate scintigraphy in the examination of patients with suspected skeletal metastases. Am. J. Roentgenol. 1997;169:1655–1661
  22. Steinborn MM, Heuck AF, Filing R, Bruegel M, Gauger L, Reiser MF. Whole-body bone marrow MRI in patients with metastatic disease to the skeletal system. J. Comput. Assit. Tomogr. 1999;23:123–129
  23. Yuh WT, Zachar CK, Barloon TJ, Sato Y, Sickels WI, Hawes DR. Vertebral compression fractures: distinction between benign and malignant causes with MR imaging. Radiology. 1989;172:215–218
  24. Bhalla SK. Metastatic disease of the spine. Clin. Orthop. 1970;73:52–60
  25. Duncker CM, Carrio J, Berna L, Estorch M, Alonso C, Ojeda B, et al.  Radioimmune imaging of bone marrow in patients with suspected bone metasases from primary breast cancer. J. Nucl. Med. 1990;31:1450–1455
  26. Bourgeois P, Thimpont J, Feremans , et al.  Bone marrow scintigraphy in patients with breast cancer. Nucl. Med. Commun. 1993;13:421–428

PII: S0720-048X(01)00477-6

European Journal of Radiology
Volume 43, Issue 3 , Pages 256-261 , September 2002