European Journal of Radiology
Volume 43, Issue 1 , Pages 1-5 , July 2002

Gray–white matter discrimination—a possible marker for brain damage in heat stroke?

  • Oded Szold

      Affiliations

    • General Intensive Care Unit, Tel-Aviv Sourasky Medical Center and the Sackler Faculty of Medicine, Tel-Aviv University, 6 Weizman Street, Tel-Aviv, Israel
    • Corresponding Author InformationCorresponding author. Tel.: +972-3-697-3248; fax: +972-3-560-4364
  • ,
  • Irith I. Reider-Groswasser

      Affiliations

    • Section of Neuroradiology, Department of Radiology, Tel-Aviv Sourasky Medical Center and the Sackler Faculty of Medicine, Tel-Aviv University, 6 Weizman Street, Tel-Aviv, Israel
  • ,
  • Ron Ben Abraham

      Affiliations

    • General Intensive Care Unit, Tel-Aviv Sourasky Medical Center and the Sackler Faculty of Medicine, Tel-Aviv University, 6 Weizman Street, Tel-Aviv, Israel
  • ,
  • Galit Aviram

      Affiliations

    • Section of Neuroradiology, Department of Radiology, Tel-Aviv Sourasky Medical Center and the Sackler Faculty of Medicine, Tel-Aviv University, 6 Weizman Street, Tel-Aviv, Israel
  • ,
  • Yoram Segev

      Affiliations

    • Section of Neuroradiology, Department of Radiology, Tel-Aviv Sourasky Medical Center and the Sackler Faculty of Medicine, Tel-Aviv University, 6 Weizman Street, Tel-Aviv, Israel
  • ,
  • Philippe Biderman

      Affiliations

    • General Intensive Care Unit, Tel-Aviv Sourasky Medical Center and the Sackler Faculty of Medicine, Tel-Aviv University, 6 Weizman Street, Tel-Aviv, Israel
  • ,
  • Patrick Sorkine

      Affiliations

    • General Intensive Care Unit, Tel-Aviv Sourasky Medical Center and the Sackler Faculty of Medicine, Tel-Aviv University, 6 Weizman Street, Tel-Aviv, Israel

Received 20 July 2001 ,Revised 20 October 2001 ,Accepted 25 October 2001.

References 

  1. Khogeli M, Weiner JS. Heat stroke: report on 18 cases. Lancet. 1980;2:276–288
  2. Shibolet S, Lancaster MC, Danon Y. Heat stroke: a review. Aviat. Space Environ. Med. 1974;133:841–864
  3. Dematte JE, O'Mara K, Buescher J, Whitney CG, Forsythe S, McNamee T, et al. Near-fatal heat stroke during 1995 heat wave in Chicago. Ann. Intern. Med. 1998;129:173–181
  4. Center for Disease Control. Heat-related illnesses and death—United-States, 1994–1995. MMWR Morb Mortality Wkly Rep 1995;44:465–8.
  5. Austin MG, Berry JW. Observation on one hundred cases of heatstroke. J. Am. Med. Assoc. 1956;161:1525–1529
  6. Hart GR, Anderson RJ, Crumpler CP, Shulkin A, Reed G, Knochel JP. Epidemic classical heat stroke: clinical characteristic and course of 28 patients. Medicine. 1982;61:189–197
  7. Ferris EB, Blankenhorn MA, Robinson HW, Cullen GE. Heat stroke: clinical and chemical observations on 44 cases. J. Clin. Invest. 1938;17:249–262
  8. Yaqub BA, Al-Harthi S, Al-Orainey I, Laajam M, Obeid M. Heat stroke at Mekkah pilgrimage: clinical characteristics and course of 30 patients. Q. J. Med. 1986;59:523–530
  9. Yaqub BA. Neurologic manifestations of heatstroke at the Mecca pilgrimage. Neurology. 1987;37:1004–1006
  10. Reider-Groswasser I, Segev Y, Ommaya AK, Schwab K, Salazar AM. Neuroradiologic assessment in traumatic brain injury and stroke. In: Kayhan O, Guven Z, Ozaras N, editors. Congress on Rehabilitation Medicine. Bologna: Monduzzi editore 1995:137–145.
  11. Reider-Groswasser I, Ommaya AK, Salazar AM. Neuroimaging assessment in TBI and stroke: relevance for acute and post acute treatment. In: Leon-Carrion J, editor. Neuropsychological Rehabilitation. Florida, USA: St. Lucie Press, 1997:73–108.
  12. George AE, Deleon MJ, Ferris SH, Kricheff II. Parenchymal CT correlates of senile dementia (Alzheimer disease): loss of gray–white matter discriminability. Am. J. Neuroradiol. 1981;2:205–213
  13. Groswasser Z, Reider-Groswasser I, Soroker S, Machtey Y. Magnetic resonance imaging in head injured patients with normal late computed tomography. Surg Neurol 1987;27:331–7.
  14. Thatcher RW, Camacho M, Salazar A, Linden C, Biver C, Clarke L. Quantitative MRI of the gray–white matter distribution in traumatic brain injury. J. Neurotrauma. 1997;14:1–14
  15. Kjos B, Brant-Zawadzki M, Young R. Early CT findings of global central nervous hypoperfusion. Am. J. Radiol. 1983;141:1287–1332
  16. Torbey MT, Paydarfar D, Bigelow C, Recht L. Loss of gray–white matter differentiation (GWMD) predicts poor patients outcome after cardiac arrest. Neurology. 1999;52(Suppl. 2):A6(abstract)
  17. Torbey MT, Selim M, Knorr J, Bigelow C, Recht L. Quantitative analysis of the loss of distinction between gray and white matter in comatose patients after cardiac arrest. Stroke. 2000;31:2163–2167
  18. Brooks AD, Di Chiro G, Keller MR. Explanation of cerebral white–gray contrast in computed tomography. J. Comput. Assist. Tomogr. 1980;4:489–491
  19. Hossmann KA, Schuier FJ. Experimental brain infarcts in cats, I: pathophysiological observations. Stroke. 1980;11:583–592
  20. Schuier FJ, Hossmann KA. Experimental brain infarcts in cats, II: ischemic brain edema. Stroke. 1980;11:593–601
  21. Bird CR, Drayer BP, Gilles FH. Pathophysiology of ‘reverse’ edema in global cerebral ischemia. Am. J. Neuroradiol. 1989;10:95–98
  22. Han BK, Towbin RB, De Courten-Myers G, McLaurin RL, Ball WS. Reversal sign on CT: effect of anoxia/ischemic cerebral injury in children. Am. J. Neuroradiol. 1989;10:1191–1198
  23. Benes FM, Parks TN, Rubei FW. Rapid dendritic atrophy following deafferentation. An EM morphometric analysis. Brain Res. 1977;122:1–13
  24. Povlishock JT, Kontos HA. Continuing axonal and vascular changes following experimental brain trauma. J. Cent. Nervous Syst. Trauma. 1985;2:285–298
  25. Povlishock JT, Becker DP, Cheng CY, Vaughan GW. Axonal changes in minor head injury. J. Neuropathol. Exp. Neurol. 1983;42:225–242
  26. Thomas IB, Steindler DA. Glial boundaries and scars: programs for normal development and wound healing in the brain. Neuroscientist. 1995;1:142–154
  27. Ida M, Mizunuma K, Hata Y, Tada S. Subcortical low intensity in early ischemia. Am. J. Neuroradiol. 1994;15:1387–1393
  28. Moody DM, Bell MA. Features of the cerebral vascular pattern that predict vulnerability to perfusion or oxygenation deficiency: an anatomic study. Am. J. Neuroradiol. 1990;11:431–439
  29. Albukrek D, Bakon M, Moran DS, Faibel M, Epstein Y. Heat-stroke-induced cerebellar atrophy: clinical course, CT and MRI findings. Neuroradiology. 1997;39:195–197
  30. Kinney HC, Korrein J, Panirahy A, Dikkes P, Goode R. Neuropathological findings in the brain of Karen Ann Quinlan. The role of the thalamus in the persistent vegetative state. New Engl. J. Med. 1994;330:1469–1475
  31. Kampfl A, Franz G, Aichner F, Pfausler B, Haring HP, Felber S, et al. The persistent vegetative state after close head injury: clinical and magnetic resonance imaging findings in 42 patients. J. Neurol. 1998;88:809–816
  32. Reider-Groswasser I, Costeff H, Sazbon L, Groswasser Z. CT findings in perisitent vegetative state following traumatic brain injury. Brain Injury. 1997;11:865–870

PII: S0720-048X(01)00467-3

European Journal of Radiology
Volume 43, Issue 1 , Pages 1-5 , July 2002