European Journal of Radiology
Volume 40, Issue 1 , Pages 2-9, October 2001

Effectiveness of dynamic MRI for diagnosing pericicatricial minimal residual breast cancer following excisional biopsy

  • Hiroko Kawashima

      Affiliations

    • Department of Radiology, Kanazawa University School of Medicine, 13-1 Takara-machi, Kanazawa, Ishikawa 920-8641, Japan
    • Corresponding Author InformationCorresponding author. Tel.: +81-76-265-2323; fax: +81-76-234-4256
    • ,
  • Mari Tawara

      Affiliations

    • Department of Radiology, Kanazawa University School of Medicine, 13-1 Takara-machi, Kanazawa, Ishikawa 920-8641, Japan
    • ,
  • Masayuki Suzuki

      Affiliations

    • Department of Radiological Technology, Kanazawa University School of Medicine, 5-11-80 Kodatsuno, Kanazawa, Ishikawa 0942, Japan
    • ,
  • Osamu Matsui

      Affiliations

    • Department of Radiology, Kanazawa University School of Medicine, 13-1 Takara-machi, Kanazawa, Ishikawa 920-8641, Japan
    • ,
  • Masumi Kadoya

      Affiliations

    • Department of Radiology, Shinsyu University School of Medicine, 3-1-1 Asahi, Matsumoto, Nagano 390-8627, Japan

Received 19 January 2000; received in revised form 27 January 2001; accepted 30 April 2001.

Abstract 

The purpose of this study was to investigate the effectiveness of dynamic MRI for diagnosing pericicatricial minimal residual breast cancer following excisional biopsy. Twenty-six patients who underwent excisional biopsy of a tumor or calcified lesion of the breast underwent gadolinium-enhanced dynamic MRI by the fat-saturated 2D fast spoiled gradient echo (SPGR) sequence (group 1), 24 patients by the spectral IR enhanced 3D fast gradient echo (Efgre3d) sequence (group 2). Pericicatricial residual cancer was confirmed histologically in 29 of the 50 patients. The overall sensitivity, specificity, accuracy, positive predictive value, and negative predictive value of MRI for residual cancer diagnosis was 66, 81, 72, 83 and 63%. A nodular, thick and discontinuous enhanced rim around the scar is indicative of a residual tumor. However, false-positive findings due to granulation or proliferative fibrocystic change remain limitations.

Keywords:  Dynamic MRI, Breast cancer, Excisional biopsy

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PII: S0720-048X(01)00358-8

European Journal of Radiology
Volume 40, Issue 1 , Pages 2-9, October 2001

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