European Journal of Radiology
Volume 40, Issue 1 , Pages 16-23 , October 2001

Comparative detectability of bone metastases and impact on therapy of magnetic resonance imaging and bone scintigraphy in patients with breast cancer

  • Carsten Altehoefer

      Affiliations

    • Department of Diagnostic Radiology, University Hospital Freiburg, Hugstetter Strasse 55, 79106 Freiburg, Germany
    • Corresponding Author InformationCorresponding author. Tel.: +49-761-2703837; fax: +49-761-2703831
  • ,
  • Nadir Ghanem

      Affiliations

    • Department of Diagnostic Radiology, University Hospital Freiburg, Hugstetter Strasse 55, 79106 Freiburg, Germany
  • ,
  • Stefan Högerle

      Affiliations

    • Department of Nuclear Medicine, University Hospital Freiburg, Hugstetter Strasse 55, 79106 Freiburg, Germany
  • ,
  • Ernst Moser

      Affiliations

    • Department of Nuclear Medicine, University Hospital Freiburg, Hugstetter Strasse 55, 79106 Freiburg, Germany
  • ,
  • Mathias Langer

      Affiliations

    • Department of Diagnostic Radiology, University Hospital Freiburg, Hugstetter Strasse 55, 79106 Freiburg, Germany

Received 13 October 2000 ,Revised 7 February 2001 ,Accepted 12 February 2001.

References 

  1. Landis SH, Murray T, Bolden S, et al.  Cancer statistics. CA Cancer J. Clin. 1999;49:8–31
  2. Ahmed A, Glynne-Jones R, Ell PJ. Skeletal scintigraphy in carcinoma of the breast — a ten year retrospective study of 389 patients. Nucl. Med. Commun. 1990;11:421–426
  3. Sherry MM, Greco FA, Johnson DH, Hainsworth JD. Metastatic breast cancer confined to the skeletal system. Am. J. Med. 1986;81:381–386
  4. Sherry MM, Greco A, Johnson DH, Hainsworth JD. Breast cancer with skeletal metastases at initial diagnosis. Distinctive clinical characteristics and favorable prognosis. Cancer. 1986;58:178–182
  5. Schocker JD, Brady LW. Radiation therapy for bone metastasis. Clin. Orthoped. Rel. Res. 1982;169:38–43
  6. Gilbert HA, Kagan R. Evaluation of radiation therapy for bone metastases: pain relief and quality of life. Am. J. Roentgenol. 1977;129:1095
  7. Mundy GR. Mechanisms of bone metastasis. Cancer (Suppl.). 1997;80:1547–1556
  8. Wikenheiser KA, Silberstein EB. Bone scintigraphy screening in stage I-II breast cancer: is it cost-effective?. Clevel Clin. J. Med. 1996;63:43–47
  9. GIVIO investigators. Impact of follow-up testing on survival and health-related quality of life in breast cancer patients. J. Am. Med. Assoc. 1994;271:1587–1592.
  10. Rossellini DelTurco M, Palli D, Cariddi A, Ciatto S, Pacini P, Distante V. Intensive diagnostic follow-up after treatment of primary breast cancer: a randomized trial. J. Am. Med. Assoc. 1994;271:1593–1597
  11. Kamby C, Vejborg I, Daugaard S, Guldhammer B, Dirkson H, Rossing N, et al. Clinical and radiological characteristics of bone metastases in breast cancer. Cancer. 1987;60:2524–2531
  12. Ludwig H, Kumpan W, Sinzinger H. Radiography and bone scintigraphy in multiple myeloma: a comparative analysis. Br. J. Radiol. 1983;55:173
  13. Berettoni BA, Carter JR. Current concepts review: mechanisms of cancer metastasis to bone. J. Bone Joint Disord. 1986;68:308–311
  14. Daffner RH, Lupetin AR, Dash N, Deeb ZL, Sefczek RJ, Schapiro RL. MRI in the detection of malignant infiltration of bone marrow. Am. J. Roentgenol. 1986;146:353–358
  15. Hoane BR, Shields AF, Porter BA, et al.  Detection of lymphomatous bone marrow involvement with magnetic resonance imaging. Blood. 1991;78:728–738
  16. Sanal SM, Flickinger FW, Caudell MJ, Sherry RM. Detection of bone marrow involvement in breast cancer with magnetic resonance imaging. J. Clin. Oncol. 1994;12:1415–1421
  17. Yuh WTC, Zachar CK, Barloon TJ, Sato Y, Sickels WJ, Hawes DR. Vertebral compression fractures: distinction between benign and malignant causes with MR imaging. Radiology. 1989;172:215–218
  18. Bhalla SK. Metastatic disease of the spine. Clin. Orthoped. 1970;73:52–60
  19. Reske SN, Karstens JH, Gloeckner W, Schwarz A, Steinsträsser A, Ammon J, et al. Radioimmunoimaging for diagnosis of bone marrow involvement in breast cancer and malignant lymphoma. Lancet. 1989;335:299–301
  20. Layer G, Rieker O, Dorr D, Schnakenberg D, Steudel A, Reiser M. MR tomography and bone marrow scintigraphy in the screening of skeletal metastases in patients with breast carcinoma. Fortschr. Roentgenstr. 1994;160:448–452
  21. Avrahami E, Tadmor R, Dally O, Hadar H. Early MR demonstration of spinal metastases in patients with normal radiographs and CT and radionuclide bone scans. J. Comput. Assist. Tomogr. 1989;13:598–602
  22. Algra PR, Bloem JL, Tissing H, Falke THM, Arndt JW, Verboom LJ. Detection of vertebral metastases: comparison between MR imaging and bone scintigraphy. Radiographics. 1991;11:219–232
  23. Colletti PM, Dang HT, Deseran MW, Kerr RM, Boswell WD, Ralls PW. Spinal MR imaging in suspected metastases: correlation with skeletal scintigraphy. Magn. Res. Med. 1991;9:349–355
  24. Jones AL, Williams MP, Powles TJ, Oliff JFC, Hardy JR, Cherryman G, et al. Magnetic resonance imaging in the detection of skeletal metastases in patients with breast cancer. Br. J. Cancer. 1990;62:296–298
  25. Kattapuram SV, Khurana JS, Scott JA, El-Koury GY. Negative scintigraphy with positive magnetic resonance imaging in bone metastases. Skeletal Radiol. 1990;19:113–116
  26. Gosfield E, Abass A, Kneeland B. Comparison of radionuclide bone scans and magnetic resonance imaging in detecting spinal metastases. J. Nucl. Med. 1993;34:2191–2198
  27. Haubold-Reuter BG, Duewell S, Schilcher BR, Marincek B, von Schulthess GK. The value of bone scintigraphy, bone marrow scintigraphy and fast-spin echo magnetic resonance imaging in staging of patients with malignant solid tumours: a prospective study. Eur. J. Nucl. Med. 1993;20:1063–1069
  28. Neumann K, Hosten N, Venz S. Screening for skeletal metastases of the spine and pelvis: gradient echo opposed-phase MRI compared with bone scintigraphy. Eur. Radiol. 1995;5:276–284
  29. Eustace S, Tello R, DeCarvalho V, Carey J, Wroblicka JT, Melhem R, et al. A comparison of whole-body turboSTIR MR imaging and planar 99mTc-methylene diphosphonate scintigraphy in the examination of patients with suspected skeletal metastases. Am. J. Roentgenol. 1997;169:1655–1661
  30. Altehoefer C, Blum U, Bathmann J, Wüstenberg C, Uhrmeister P, Laubenberger J, et al. Comparative accuracy of magnetic resonance imaging and immunoscintigraphy for detection of bone marrow involvement in patients with malignant lymphoma. J. Clin. Oncol. 1997;15:1754–1760
  31. Petren-Mallmin M, Andreasson I, Nyman R, Hemmingsson A. Detection of breast cancer metastases in the cervical spine. Acta Radiol. 1993;34:543–548

PII: S0720-048X(01)00313-8

European Journal of Radiology
Volume 40, Issue 1 , Pages 16-23 , October 2001